Para descargar esta imagen, cree una cuenta . Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas. What Are Side Effects Associated with Using Lycopene? Exp Biol Med (Maywood). J Nutr. Lycopene. Illustration of lycopene, ketchup, atomic - 122405958 J Nutr 1992; 122:2161-2166. jQuery("#footnote_plugin_tooltip_44").tooltip({ tip: "#footnote_plugin_tooltip_text_44", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });, lower susceptibility to oxidative stress of lymphocytes 45 Porrini M, Riso P. Lymphocyte lycopene concentration an DNA protection from oxidative damage is increased in women after a short period of tomato consumption. J Food Comp Anal. J Nutr. J Nutr. It is found in intensive concentrations in the testes and seminal plasma and decreased levels have been demonstrated in men … What Are Warnings and Precautions for Lycopene? 2000; 154:201-210. jQuery("#footnote_plugin_tooltip_66").tooltip({ tip: "#footnote_plugin_tooltip_text_66", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Arch Biochem Biophys 1996; 336:1-9. jQuery("#footnote_plugin_tooltip_36").tooltip({ tip: "#footnote_plugin_tooltip_text_36", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });, even though the similarity of the chemical structure of its metabolite, with acyclo-retinoic acid, could suggest the existence of common receptors 37 Mein JR, Lian F, Wang XD. Catalogue Number: L487500: Chemical Name: Lycopene: Synonyms: ψ,ψ-Carotene; all-trans-Lycopene; C.I. 2005; 1719:146-160. jQuery("#footnote_plugin_tooltip_68").tooltip({ tip: "#footnote_plugin_tooltip_text_68", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Lycopene is a chemical molecular formula. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Lycopene has no known serious interactions with other drugs. When the production of reactive species greatly out- strips the compensating potential of the antioxidant barrier, damage cannot be avoided. Lycopene supplementation inhibits lung squamous metapla- sia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in ciga- rette smoke-exposed ferrets. Lycopene is a symmetrical tetraterpene assembled from eight isoprene units. In particular, it has been shown that supplementation of the diet with lycopene significantly increases the activation of enzymes such as glutathione reductase, glutathione S-transferase and quinone reductase 66 Breinholt V, Lauridsen ST, Daneshvar B, Jakobsen J. Doseresponse effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat. Dosage Considerations – Should be Given as Follows: This document does not contain all possible side effects and others may occur. J Nutr. Biological activity of lycopene metabolites: implications for can- cer prevention. Those aside, there are zero additional ingredients, making this an excellent choice for lycopene. Dietary factors that affect the bioavailability of carotenoids. Lycopene is a more potent inhibitor of human cancer cell proliferation than either alpha-carotene or beta-carotene. Chemical name Common names and synonyms CAS number EC number; lycopene: lycopene: 502-65-8: none: European Inventory of Existing Commercial Chemical Substances (EINECS) Listed. 10 Canene-Adams K, Campbell JK, Zaripheh S, et al. LYCOPENE - chemical information, properties, structures, articles, patents and more chemical data. In the stomach, transforms of lycopene are converted to cis 22 Re R, Fraser PD, Long M, et al. lycopene new name, Find Quality lycopene new name and Buy lycopene new name from Reliable Global lycopene new name Suppliers from mobile site on m.alibaba.com Toxicol In Vitro. Lycopene present in the human body is not synthesised lo- cally but comes from the diet. Lycopene touches our lives from before they are fully our own and well into early childhood. This potential activity is therefore worth further study. Exp Biol Med (Maywood). Lycopene: chemistry, biology, and implications for human health and disease. From a chemical viewpoint, lycopene is a carotenoid, an acyclic isomer of ╬▓-carotene. It was in- troduced to Europe in 1540 by Hern├ín Cort├®s. The tomato goes under the official scientific name of Solanum lycopersicum. J Nutr. It has been shown to display the highest scavenging capacity of all the natural carotenoids against free radicals in vitro 40 Miller NJ, Sampson J, Candeias LP, et al. Compare Products: Select up to 4 products. This information does not contain all possible interactions or adverse effects. Content and isomeric ratio of lycopene in food and hu- man plasma. Encuentre los fabricantes de Licopeno Alimentos Químicos de alta calidad, proveedores de Licopeno Alimentos Químicos y productos Licopeno Alimentos Químicos al mejor precio en Alibaba.com 59 Levy J, Bosin E, Feldman B, et al. Chemical structure of lycopene. This is because all lycopene configurations are insoluble in water but the compound dissolves in oils as it is a non-polar compound. ไลโคปีน (Lycopene) คือ สารประกอบในกลุ่มแคโรทีนอยด์ (carotenoid) ชนิดหนึ่งใน 600 ชนิด มีรงควัตถุ (Pigment ) สีแดง ละลายได้ดีในไขมันแหล่งที่พบ และขนาดรับประทาน Click to enlarge. Lycopene is the most predominant carotenoid in human plasma, present naturally in greater amounts than beta-carotene and other dietary carotenoids. In nature, lycopene occurs in the trans isomeric form, which is the thermodynamically most stable form 5 Nguyen ML, Schwartz SJ. ", Avoid use of lycopene during pregnancy or while. 2008; 66:667-83. jQuery("#footnote_plugin_tooltip_30").tooltip({ tip: "#footnote_plugin_tooltip_text_30", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Product Name: Lycopene Company Name: Cayman Chemical Company 1180 E. Ellsworth Rd. Iniciar sesión. Lycopene is a carotenoid − a natural pigment that gives some vegetables and fruits their red color. Am J Clin Nutr. See additional information. High lycopene foods include guavas, cooked tomatoes, watermelon, grapefruit, papaya, sweet red peppers, persimmon, asparagus, red cabbage, and mangos. Lycopene is one of 600 known carotenoids found in plants, deposited as elongated, needle-like crystals in mature fruit. Molecule of the week - Lycopene - Free download as Word Doc (.doc), PDF File (.pdf), Text File (.txt) or read online for free. 2000; 130:503-506. jQuery("#footnote_plugin_tooltip_19").tooltip({ tip: "#footnote_plugin_tooltip_text_19", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 20 Porrini M, Riso P, Testolin G. Absorption of lycopene from single or daily portions of raw and processed tomato. 2012; 59:1-4. jQuery("#footnote_plugin_tooltip_74").tooltip({ tip: "#footnote_plugin_tooltip_text_74", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Products originating from CMO-II are short-chain aldehydes known as apo-lycopenals which can undergo oxidation (lycopenols) or reduction 35 Mein JR, Lian F, Wang XD. Some studies on lycopene distri bution in tomatoes have shown that the epicarp and the pericarp are the parts richest in this carotenoid 12 DÔÇÖSouza MC, Singha S, Ingle. The Bottom Line. 2007; 458:136-40. jQuery("#footnote_plugin_tooltip_29").tooltip({ tip: "#footnote_plugin_tooltip_text_29", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Are the health attributes of lycopene related to its antioxidant function? Also found in cell membranes and plays an effective role in maintaining the cell’s integrity when it is under assault by toxins. Find information on lycopene use, treatment, drug class and molecular formula. From a chemical viewpoint, lycopene is a carotenoid, an acyclic isomer of ╬▓-carotene. This energy can be dissipated in the form of heat into the surrounding aqueous environ- ment or destroy the carotenoid itself. Vector illustration on isolated background. The tomato as a functional food. 1999; 69:712-718. jQuery("#footnote_plugin_tooltip_46").tooltip({ tip: "#footnote_plugin_tooltip_text_46", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); and reduce LDL oxidation or lipid peroxidation 47 Agarwal S, Rao AV. 2005; 135:1226-30. jQuery("#footnote_plugin_tooltip_10").tooltip({ tip: "#footnote_plugin_tooltip_text_10", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Unlike ╬▓-carotene, lycopene is not converted by the body to vitamin A and must therefore express its functions using different mechanisms from the latter 36 Stahl W, Sies H. Lycopene: A biologically important carotenoid for humans? Botanical Source: Tomato Red brown powder Molecular formula: C40H56 Molecular weight: 536.85 5%~95% HPLC It has a function of prevent aging and cancer. More than 80% of lycopene occurring in the human body comes from the consumption of the tomato or its by-products (sauces, juices, concentrates, etc.) This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. of certain types of cancer: – Apoptosis: although little data is available, in vivo studies have indicated that lycopene induces apoptosis in cancer cells 51 Bowen P, Chen L, Stacewicz-Sapuntzakis M, et al. The enzymatic metabolism of carotenoids is primarily catalysed by two mono-oxygenases: carotene-15,15ÔÇÖ-monoxygenases (CMO-I) and carotene-9ÔÇÖ,10ÔÇÖ-monooxygenase (CMO-II). Biological activity of lycopene metabolites: implications for can- cer prevention. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Cancer Lett. It can enhance immunity, improve atherosclerosis and anti UV radiation. Research suggests that women with higher levels of lycopene cleared oncogenic HPV in an average of 8.5 months compared to 11-12 months in women with lower levels. 2000; 130:503-506. jQuery("#footnote_plugin_tooltip_21").tooltip({ tip: "#footnote_plugin_tooltip_text_21", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Biological activity of lycopene metabolites: implications for can- cer prevention. Absorption, metabolism, and transport of carotenoids. EC Inventory: Listed. Endocr Relat Cancer. *Please select more than one item to compare 2005; 53:7371-6. jQuery("#footnote_plugin_tooltip_1").tooltip({ tip: "#footnote_plugin_tooltip_text_1", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 2 Lugasi A, Biro L, Hovarie J, et al. Oncogene. J Agric Food Chem. We do not know that it is ONLY the lycopene lowering cancer risk. J Nutr 1992; 122:2161-2166. jQuery("#footnote_plugin_tooltip_8").tooltip({ tip: "#footnote_plugin_tooltip_text_8", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 9 Schierle J, Bretzel W, Buhler I, et al. Slideshow: Cancer lifestyle risks in the UK, See "What Are Side Effects Associated with Using Lycopene? Preliminary evidence suggests a significant clinical response with use of lycopene for oral leukoplakia. Cancer Res. Technical details about Lycopene, learn more about the structure, uses, toxicity, action, side effects and more – Gap junctions: these channels present between cells allow the ex- change of nutrients, breakdown products and information. 2007; 137:1493-5. jQuery("#footnote_plugin_tooltip_39").tooltip({ tip: "#footnote_plugin_tooltip_text_39", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); are produced. Lycopene. Lycopene is a naturally occurring chemical that gives fruits and vegetables a red color. Buy highly pure Lycopene, CAS No : 502-65-8, Mol. Tomatoes contain a chemical called lycopene, which is thought to play a role in preventing cancer. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. One of the biggest benefits of lycopene is that it is an antioxidant and protects the body of damage from free radical stress, which can hurt DNA and other cell structures. It contains 13 double bonds, of which 11 are conjugated. Each extension in this conjugated systemreduces the energy re… Acta Biochim Pol. As with other carotenoids, the double bonds in lycopene can undergo isomerization from trans to mono or poly- cis isomers by light, thermal energy, and chemical reactions. Check price at AmazonNOW Lycopene keeps it basic, but this formulation has a solid dosage of 20 mg of lycopene per capsule, which is delivered in rice bran oil and a gelatin capsule. J Med Food. M. Lycopene concentration of tomato fruit can be estimated from chromaticity values. Taking Lycopene either naturally or as a supplement is believed to be linked in helping prevent some major diseases while contributing to overall health. 320 Siepo Chwastowsa-Siwieca I Kondratowic Miulsi The Effect of Lycopene Addition on the Chemical Composition, Sensory Attributes and Physicochemical Nutr Rev. Lycopene for food use is also manufactured by chemical synthesis or produced by fermentation of Blakeslea trispora. 2000; 92:1472-89. jQuery("#footnote_plugin_tooltip_71").tooltip({ tip: "#footnote_plugin_tooltip_text_71", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Lycopene gets its color and antioxidant properties from its chemical structure, which consists of a long chain of eleven conjugated double bonds. Loss of carotene-9′,10′-monooxygenase expression in- creases serum and tissue lycopene concentrations in lycopene-fed mice. Int J Vitam Nutr Res. 1999; 53:38-45. jQuery("#footnote_plugin_tooltip_5").tooltip({ tip: "#footnote_plugin_tooltip_text_5", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 6 Zechmeister L, LeRosen AL, Went FW, Pauling L. Prolycopene, a naturally occurring stereoiso- mer of lycopene. The latter can form by oxidation due to free radicals, to lipoxygenase activity, to phase II detoxifying enzymes or carotenoid cleavage enzymes 30 Mein JR, Lian F, Wang XD. Having a chemical formula of C40H56, lycopene is a tetraterpene assembled from eight isoprene units that … J Biol Chem. Lycopene is an antioxidant found in red and pink fruits that has been linked to various beneficial effects. Food Technol. Carotenoid content of selected Indonesian fruits. 1996; 10:542-51. jQuery("#footnote_plugin_tooltip_27").tooltip({ tip: "#footnote_plugin_tooltip_text_27", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. More studies are needed to determine effectiveness. 2002; 227:914-9. jQuery("#footnote_plugin_tooltip_25").tooltip({ tip: "#footnote_plugin_tooltip_text_25", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 26 Gugger ET, Erdman JW Jr. Intracellular beta-carotene transport in bovine liver and intes- tine is not mediated by cytosolic proteins. More research is needed to determine that. The influence of lycopene on the proliferation of hu- man breast cell line (MCF-7). Lists the various brand names available for medicines containing lycopene. Lycopersicum (wolf peach) is the Latin expression that gave rise to the term lycopene. Tomato lycopene and low density lipoprotein oxidation: a human di- etary intervention study. Lycopene is the scientific name for the red carotenoid pigment that is found in blood. 2010; 140(12):2134-8. jQuery("#footnote_plugin_tooltip_33").tooltip({ tip: "#footnote_plugin_tooltip_text_33", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Metabolites in determining their numerous biological activities ( Figure 3 ) our lives from they. Protecting cells against the damaging effects of free radicals, apricots,,... At the health attributes of lycopene for oral leukoplakia from chromaticity values ) is the name... Foods containing lycopene vegetables a red color, get medical help or contact a Poison Control Center.... Its name is derived from the oxidative metabolism of macronutrients introduced in the same as. 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