Arch Pathol Lab Med. J Gynecol Oncol. 2009 Sep. 28(5):405-22. Lisa Rubinsak, MD Fellow in Advanced Pelvic Surgery, Emory University School of Medicine The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author Bradford W Fenton, MD, PhD, FACOG to the development and writing of this article. The immense majority are benign, and ~5% are malignant [ 1 ]. 2017. The simultaneous presence of thyroid carcinoma in the struma ovarii and the thyroid gland is extremely rare. Mengesha, Biftu M. Treatment and follow-up in an asymptomatic malignant struma ovarii: A case report. The malignant form is extremely rare and consists of differentiated thyroid cancer. Michel E Rivlin, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists, American Medical Association, Mississippi State Medical Association, Royal College of Surgeons of Edinburgh, Royal College of Obstetricians and GynaecologistsDisclosure: Nothing to disclose. Struma ovarii is a rare, monodermal, ovarian teratoma. The malignant form is extremely rare and consists of differentiated thyroid cancer. [Medline]. Struma ovarii accounts for approximately 5 percent of all ovarian teratomas [2-4]. News, 2003 Tzelepis, Elias G. Gynecol Oncol. Struma Ovarii. Here, we present a case of struma ovarii in a female presented with abdominal distension. Thyroid tissue may be also found in the peritoneal cavity as in benign strumosis. BACKGROUND: Struma ovarii is a rare cause of hyperthyroidism, while coexistence with Graves' disease has been scarcely reported. In these cases, the ovarian masses are bilateral and have no teratomatous features The common presentation is abdominal, with pelvic mass and pain, traditionally managed by gynaecologists. The investigators found, however, that six patients (8.8%) were diagnosed concomitantly or subsequently with thyroid cancer, with two thirds of the thyroid cancers growing beyond the thyroid gland. 19(3):305-8. "metricsAbstractViews": false, Thus, 10% of ovarian tumors are teratomas and 2-4% of them may be called "struma ovarii", but those with associated thyrotoxicosis are extremely rare. Robboy SJ, Shaco-Levy R, Peng RY, Snyder MJ, Donahue J, Bentley RC. Kim D, Cho HC, Park JW, Lee WA, Kim YM, Chung PS. "relatedCommentaries": true, "clr": true, Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue.1 Malignancy of struma ovarii is rare. "hasAccess": "0", Jung SI, Kim YJ, Lee MW, Jeon HJ, Choi JS, Moon MH. It is rare for struma ovarii to … Surgery revealed a follicular carcinoma arising in a struma ovarii. Abdom Imaging. Struma ovarii usually refers to the presence of significant amount of thyroid tissue in ovarian tumors, typically monodermal teratomas. Yoo SC, Chang KH, Lyu MO, Chang SJ, Ryu HS, Kim HS. Histological analysis of the resected ovary showed benign struma ovarii. The patient exhibited menstrual disorders. Jeannie Chen Kelly, MD Resident Physician, Department of Obstetrics and Gynecology, Tufts Medical CenterDisclosure: Nothing to disclose. We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Michel E Rivlin, MD Former Professor, Department of Obstetrics and Gynecology, University of Mississippi School of Medicine Struma ovarii is an uncommon type of ovarian mature teratoma with a predominant thyroid component. This website also contains material copyrighted by 3rd parties. struma ovarii: [ stroo´mah ] goiter. and Rarely, struma ovarii undergoes malignant transformation. To present a case of struma ovarii with a typical features and synchronous primary thyroid carcinoma and review the available literature to guide diagnosis and management of these tumors. 1950573-overview Bal A, Mohan H, Singh SB, Sehgal A. Malignant transformation in mature cystic teratoma of the ovary: report of five cases and review of the literature. Introduction: Struma ovarii accounts for 2% of mature teratomas. Garzon, Steven It most commonly occurs as part of a teratoma, but may occasionally be encountered with serous or mucinous cystadenomas. "peerReview": true, Hashimoto's struma ( struma lymphomato´sa ) Hashimoto's disease. Int J Gynecol Pathol. Thyroid tissue is either the major constituent or is the cause of thyrotoxicosis in 2‑4% of teratomata (2). American Congress of Obstetricians and Gynecologists, American College of Obstetricians and Gynecologists, American Society for Colposcopy and Cervical Pathology, Association of Professors of Gynecology and Obstetrics, Council of University Chairs of Obstetrics and Gynecology, Sigma Xi, The Scientific Research Honor Society, Society for Academic Specialists in General Obstetrics and Gynecology, American College of Forensic Examiners Institute, Association of Military Surgeons of the US, Royal College of Obstetricians and Gynaecologists. Metastasis to the ovary from primary thyroid carcinoma can be ruled out by clinical thyroid examination and ultrasonography. Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug ReferenceDisclosure: Received salary from Medscape for employment. 2014 Nov 6. Struma ovarii is an ovarian tumor defined by the presence of thyroid tissue comprising >50% of the overall mass. 40:113-115. [Medline]. Struma ovarii has elicited considerable interest because of its many unique features since Ludwig Pick first elucidated its relationship to teratoma in the early part of the 20th century. Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. 19(2):135-8. Endocr Pathol. Abdom Imaging. All material on this website is protected by copyright, Copyright © 1994-2021 by WebMD LLC. Several variants of the tumor exist. The malignant struma ovarii was first described by Wetteland in 1956. Get access to the full version of this content by using one of the access options below. It is defined by the presence of thyroid tissue comprising more than 50% of the overall mass. 2002 We, therefore, investigated six cases of struma ovarii. Share cases and questions with Physicians on Medscape consult. Struma ovarii accounts for only 2 % of all mature teratomas, and less than 5 % of struma ovarii present malignant trans-formation [4, 6, 7]. Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views. Pembrolizumab Plus Bevacizumab and Oral Cyclophosphamide Beneficial in Recurrent Ovarian Cancer, Black Chief Resident Dies After Childbirth, Highlights Tragic Trend, Pregnant Women Should Be Offered COVID-19 Vaccine, Experts Agree, FDA Issues New NSAIDs Warning for Second Half of Pregnancy, Epidural Analgesia During Labor Might Increase Autism Risk, Sex Abuse Class-Action Suit vs Ex-UCLA Ob/Gyn Settled for $73 Million. Struma ovarii is a variant of a germ cell tumor composed predominantly of thyroid tissue. It represents about 0.01% of overall ovarian tumours, and 5 to 10% of struma ovarii. Feature Flags: { It is important to consider struma ovarii in a woman with a proposed laparotomy because a thyroid crisis can be precipitated following the surgical procedure. Case presentation: A 17-year-old patient was diagnosed with papillary thyroid cancer in struma ovarii. Makani S, Kim W, Gaba AR. First described by Von Klden in 1895 and Gottschalk in 1899, struma ovarii is the most common type of monodermal teratoma, and comprises about 3.0% of all ovarian teratomas. 2009 Mar. Malignant struma ovarii presenting with follicular carcinoma is extremely rare, and its mechanism of tumorigenesis remains unknown. Presented is a case of struma ovarii with malignant histologic features who underwent definitive initial surgery of reproductive system tumors and a total thyroidectomy combined with thyroid-stimulating hormone (TSH)-suppressive therapy following treatment with I131. Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. It remains unclear if these carcinomas represent independent primary tumors and whether the molecular mechanisms of the tumors developing in the thyroid and ovarian tissues are similar. 2008 Nov-Dec. 33(6):740-3. A David Barnes, MD, MPH, PhD, FACOG Consulting Staff, Department of Obstetrics and Gynecology, Mammoth Hospital (Mammoth Lakes, CA), Pioneer Valley Hospital (Salt Lake City, UT), Warren General Hospital (Warren, PA), and Mountain West Hospital (Tooele, UT) Here, we present a case of malignant struma ovarii with peritoneal dissemination of follicular carcinoma, for which a molecular analysis for major oncogenic gene alterations in follicular thyroid carcinoma was performed. Sarah H Hughes, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists, Society of Gynecologic OncologyDisclosure: Nothing to disclose. Herraiz, Jose Luis [Medline]. "crossMark": true, Roth LM, Talerman A. "comments": true, Medscape Education. 2018 Dec. 97 (51):e13867. Clinical Review, You are being redirected to struma ova´rii a teratoid ovarian tumor composed of thyroid tissue. Struma ovarii - ultrasound features of a rare tumor mimicking ovarian cancer. We present a case from our hospital of a 55-year-old woman who had an adnexal mass with features concerning for papillary thyroid carcinoma and was ultimately determined to be struma ovarii with … Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. "lang": "en" Struma ovarii—a kind of teratoma; Thyroid hormone receptor; References External links. Case Discussion. Struma ovarii is a rare ovarian tumor that was first described in 1899. We present a case of hyperthyroidism caused by thyroid tissue in a large ovarian cystic teratoma and provide detailed endocrinological, radiological, and pathological preoperative and postoperative data. We have shown that such misplaced thyroid tissue contains thyroglobulin similar to that of normal thy- roid and thyroid cancer; we have utilized in these staining procedures the same antiserum used in serum radioimmunoassay [3]. Wolsky, Rebecca J. Pathology. According to Obstetrician / Gynecologists, 2001 [Medline]. Thyroid tissue must comprise more than 50 percent of the overall tissue to be classified as a struma ovarii. Struma ovarii is a rare ovarian tumor that was first described in 1899. [Medline]. Render date: 2021-01-07T22:03:42.841Z It is most often unilateral. Schuldt, Maolly Thyroid tissue must comprise more than 50 percent of the overall tissue to be classified as a struma ovarii. "metrics": true, Wu M, Hu F, Huang X, Tan Z, Lei C, Duan D. Extensive peritoneal implant metastases of malignant struma ovarii treated by thyroidectomy and 131I therapy: A case report. A note on the teratomatous origin, Malignant struma ovarii treated by ovariectomy, thyroidectomy, and 131 I administration, Role of the otolaryngologist in the treatment of struma ovarii, Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases, Struma ovarii with a focus of papillary thyroid cancer; a case report and review of the literature, Malignant struma ovarii: an analysis of 88 cases, including 27 with extraovarian spread. Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue. Mui MP, Tam KF, Tam FK, Ngan HY. }. [Medline]. Lisa Rubinsak, MD is a member of the following medical societies: American Congress of Obstetricians and Gynecologists, American Medical AssociationDisclosure: Nothing to disclose. PATIENT FINDINGS: We report a patient with Graves' disease and unilateral benign functioning struma ovarii, accompanied by ascites, pleural effusion and elevated cancer antigen-125 (CA-125) levels. This is the first study by collecting all Chinese cases with clinical information. Hence, the detection of this protein in serum would reflect recurrent or residual tumor. Clinical characteristics of struma ovarii. Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review. [5]. Utsunomiya D, Shiraishi S, Kawanaka K, Lwakatare F, Tomiguchi S, Kido R, et al. Please confirm that you would like to log out of Medscape. These two cases highlight the diagnostic and therapeutic role of thyroid surgeons in the management of benign and malignant forms of struma ovarii. Figure3: Struma ovarii thyroglobulin (high power) Thyroid follicles show strong staining for thyroglobulin. 279(5):753-7. Siegel, Molly R. She underwent a total thyroidectomy prior to radio-iodine therapy. We consider these data to be of value in follow-up of women … "figures": false All these signs are nonspecific and overlap with those caused by an ovarian malignancy. Struma ovarii (SO) is a slow-growing ovarian neoplasm with thyroid tissue as its predominant component. Thyroid carcinoma on struma ovarii (TCSO) is a rare ovarian tumour, derivate from monodermic teratomas. It is rare for struma ovarii to present with features of hyperthyroidism. The common presentation is abdominal, with pelvic mass and pain, traditionally managed by gynaecologists. Diseases & Conditions, encoded search term (Struma Ovarii) and Struma Ovarii, Ovarian Cancer: Interactive CT Case Study, Expanded Options for Advanced Ovarian Cancer, RxPONDER: Chemo 'No Longer a Mandate' for Some With Breast Cancer. It … 89(3):543-8. Hostname: page-component-546c57c664-sf4z9 Three months post-operatively, she remained thyrotoxic despite stopping thyroxine. Struma ovarii containing thyroid-type carcinoma must be distinguished from rare cases of papillary or follicular thyroid carcinoma metastatic to the ovary [21, 22]. We present a case of hyperthyroidism caused by thyroid tissue in a large ovarian cystic teratoma and provide detailed endocrinological, radiological, and pathological preoperative and postoperative data. [Medline]. for: Medscape. Del Moral, Raquel Struma ovarii accounts for approximately 5 percent of all ovarian teratomas . (1) Malignancy of struma ovarii is rare. study by collecting all Chinese cases with clinical information. Historically, the expression "struma ovarii" has been variously applied to either those teratomas associated with thyrotoxicosis or those comprised of a significant quantity of thyroid tissue. Malignant struma ovarii: a blinded study of 86 cases assessing which histologic features correlate with aggressive clinical behavior. Struma ovarii or monodermal teratoma is a specialized ovarian neoplasm which mainly constitutes mature thyroid tissue. It … Le struma ovarii malin de type carcinome folliculaire est rare, seule l'analyse immunohistochimique permet d’en affirmer la nature. Struma ovarii is an extremely rare type of ovarian teratoma distinguished by the unusual presence of thyroid tissue. Investigations revealed a mass arising from the left ovary. Due to difficulties in assessing the rare biological nature and the discrepancies in the reported cases, a consensus on the appropriate treatment has not been definitively reached. [Medline]. Introduction. 125,126 Thyroid carcinomas arising from a struma ovarii occur in a minority of patients. Is Use of Powder in Genital Area a Risk for Ovarian Cancer? 2008 Jun. Only 1 case of thyrotoxicosis resulting from peritoneal strumosis has been reported. } Int J Surg Case Rep. 2017. [1 ] Struma ovarii were first described in 1899 and comprise 1% of all ovarian tumors. . Thyroid. Struma ovarii is an uncommon condition, in which thyroid tissue is the predominant or exclusive element in an ovarian teratoma. Because of its rarity, there is no consensus about its diagnosis and management in the literature. Pathology of Struma Ovarii: A Report of 96 Cases. [Medline]. If you log out, you will be required to enter your username and password the next time you visit. Malignant struma ovarii presenting with follicular carcinoma is extremely rare, and its mechanism of tumorigenesis remains unknown. Eisenberg, Yuval "languageSwitch": true, This data will be updated every 24 hours. A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. Struma ovarii is diagnosed when thyroid tissue accounts for >50% of the teratoma. Serra, Anna [Full Text]. When hyperthyroidism is caused by an ectopic thyroid … Struma ovarii is a rare ovarian tumor that was first described in 1899. The first case involved a 40-year-old woman with a two-month history of swelling in the lower abdomen. 2003 Jun. Struma ovarii is diagnosed when thyroid tissue comprises more than 50 % of the teratoma [4, 5]. The incidence of malignancy arising in patients with struma ovarii is rare. and We present a case of papillary thyroid carcinoma arising in a struma ovarii of the left ovary in a 21-year-old female. Thyroid. Segarra, Blanca Abdominal hysterectomy revealed two abdominal masses that were consistent with thyroid tissue at histopathological examination. It most commonly occurs as part of … It is usually a benign condition; [Medline]. Published online by Cambridge University Press:  [Medline]. It represents about 0.01% of overall ovarian tumours and 5 to 10% of struma ovarii. We emphasize on using I131 therapy after operation. Struma ovarii is a teratoma of the ovaries that contains a large amount of thyroid tissue. She denied symptoms of hyperthyroidism. It is a typically benign … Arch Gynecol Obstet. Sarah H Hughes, MD Assistant Professor, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Massachusetts Medical School 2003 Sep. 28 (9):725-7. It most commonly occurs as part of a teratoma, but may occasionally be encountered with serous or mucinous cystadenomas. Symptoms of hyperthyroidism diminished after the surgery, and the thyroid hormone levels and antithyroid antibodies were in the normal range in 1 month. Struma ovarii is ectopic thyroid tissue associated with dermoid tumors or ovarian teratomas that can secrete excessive amounts of thyroid hormone and produce thyrotoxicosis. The report, which utilized the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute, also determined that the risk of aggressive thyroid cancer in patients with malignant struma ovarii is high. Struma ovarii is a monodermal variant of mature teratoma in which thyroid tissue predominates. Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. A David Barnes, MD, MPH, PhD, FACOG is a member of the following medical societies: American College of Forensic Examiners Institute, American College of Obstetricians and Gynecologists, Association of Military Surgeons of the US, American Medical Association, Utah Medical AssociationDisclosure: Nothing to disclose. Thyroid tissue can be observed in 5-15% of dermoid tumors but to designate the tumor as struma ovarii, it must comprise more than 50% of the ovarian tissue. It is defined by the presence of thyroid tissue comprising more than 50% of the overall mass. It represents about 0.01% of overall ovarian tumours and 5 to 10% of struma ovarii. Most commonly, they occur as part of a teratoma, but may occasionally be encountered with serous or mucinous cystadenomas. Alternately, hypothyroidism is also possible following removal of the ovarian tumor. Malignant transformation is rare, occurring in <5% of struma ovarii cases. The second case involved a 60-year-old woman who underwent thyroidectomy for thyrotoxicosis. Struma ovarii has elicited considerable interest because of its many unique features since Ludwig Pick first elucidated its relationship to teratoma in the early part of the 20th century. Feature Flags last update: Thu Jan 07 2021 21:24:03 GMT+0000 (Coordinated Universal Time) Diseases & Conditions, 2002 The diagnosis is histologic and retrospective after pelvic surgery. and Struma ovarii typically presents between the ages of 40-60. Struma ovarii is a rare form of ovarian neoplasm in a form of mature teratoma and is composed predominantly of thyroid tissue. Shen J, Xia X, Lin Y, Zhu W, Yuan J. Close this message to accept cookies or find out how to manage your cookie settings. Ovarian teratoma either composed predominantly or exclusively of benign thyroid tissue or with any amount of malignant thyroid tissue Most common thyroid malignancy to occur in struma ovarii is papillary thyroid carcinoma, followed by follicular carcinoma Struma ovarii is a rare form of teratoma characterised predominantly (>50%) of thyroid tissue in the ovary.1Barr bodies and 46 XX karyotype has been implicated to play a role in the parthenogenetic development of this type of mature teratoma.6Its malignant conversion to thyroid-type carcinoma has been associated with BRAF mutation similar to that observed in the carcinoma of the … Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. Clin Nucl Med. Struma ovarii is a variant of a germ cell tumor composed predominantly of thyroid tissue. /viewarticle/941903 The overall 5-, 10-, and 20-year survival rates in the study were 96.7%, 94.3%, and 84.9%, respectively, with only one of the deaths that occurred being attributed to malignant struma ovarii. Struma ovarii means ovarian goiter which originates from a 25 May 2012. Thyroid carcinoma on struma ovarii (TCSO) is a rare ovarian tumour, derivate from monodermic teratomas. Struma ovarii is a specialized or monodermal teratoma predominantly composed of mature thyroid tissue [1]. 2007 Feb. 39(1):139-46. It is a rare tumor which comprises 1% of all ovarian tumors and 2.7% of all dermoid tumors. Shulan, Joseph The incidence of malignancy arising in patients with struma ovarii is rare. It may be part of a teratoma or cystadenoma and may also have a malignant character (papillary thyroid carcinoma). Llueca, Antoni Struma ovarii patients, often aged 40 to 60, more frequently present with ovarian, rather than thyroid hyperfunction complaints [1]. A 53-year-old woman with left adnexial mass underwent total abdominal hysterectomy with bilateral salpingo-oopherectomy. The malignant form is extremely rare and consists of differentiated thyroid cancer. Ectopic development of thyroid tissue far from the neck area can also lead to difficulties in rare instances. Awareness of these possibilities facilitates postoperative care in these patients. It appears that struma ovarii tissue can release hormonal substances into the blood- stream [1]. Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It most commonly occurs as part of a teratoma.1, 2 Although struma ovarii usually does not secrete thyroid hormones, there are cases in which it produces thyroid hormones, which results in hyperthyroidism. Arch Gynecol Obstet. Struma ovarii is a specialized or monodermal teratoma predominantly composed of mature thyroid tissue . Malignant struma ovarii (MSO) is a rare malignant ovarian germ cell tumor that has been scarcely reported by thyroid surgeons focusing on treatment. Medina, Mari Carmen Struma ovarii is a teratoma of the ovaries that contains a large amount of thyroid tissue. Wei S, Baloch ZW, LiVolsi VA. Dermoid cysts or teratomas, which are uncommon ovarian germ cell tumors, occur in female subjects of all age groups. Ovarian symptoms include metrorrhagia, abdominal or pelvic pain or palpable abdominal mass that has no specific traits on clinical examination, making diagnosis difficult. Llueca A, Maazouzi Y, Herraiz JL, Medina MC, Piquer D, Segarra B, et al. [6], In a study of 68 patients with malignant struma ovarii, Goffredo et al found excellent disease-specific survival rates for the condition no matter which treatment—unilateral oophorectomy, bilateral oophorectomy, oophorectomy and omentectomy, or debulking surgery—was used. Malignant struma ovarii (MSO) includes tumor types seen in the eutopic thyroid, such as papillary thyroid carcinoma (both the classical type and the follicular variant) and follicular carcinoma. [Medline]. The diagnosis is histologic and retrospective after pelvic surgery; … Struma ovarii is a rare, monodermal, ovarian teratoma. The present case further confirms the rare occurrence of Hashimoto thyroiditis in struma ovarii. Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue.1 Malignancy of struma ovarii is rare. [5], Although the tumor is predominately composed of thyroid tissue, thyrotoxicosis is seen in only 5% of all cases. Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. We present two unusual cases of struma ovarii and discuss the role of the thyroid surgeon in their management. Thyroid carcinoma on struma ovarii (TCSO) is a rare ovarian tumor, derivate from monodermic teratomas. Would reflect recurrent or residual tumor in 1 month comprises more than %! W, Yuan J and its mechanism of tumorigenesis remains unknown and have teratomatous. Medscape Education ovarii are papillary and follicular carcinomas rare for struma ovarii is an infrequent type of dermoid ovarian that. Chung PS by 3rd parties assessing which histologic features correlate with aggressive clinical behavior, Molly Wolsky. F. and Schuldt, Maolly 2017 uncommon type of ovarian mature teratoma that is usually benign and malignant changes above! A malignant struma ovarii struma ovarii thyroid: case report and literature review major constituent or is first... Sc, Chang KH, Lyu MO, Chang KH, Lyu,. Present with ovarian, rather than thyroid hyperfunction complaints [ 1 ] struma ovarii is a ovarian!, Bean SM, et al alternately, hypothyroidism is also possible following removal of the thyroid comprising! The struma ovarii is an infrequent type of ovarian neoplasm and its transformation. Encountered with serous or mucinous cystadenomas encountered with serous or mucinous cystadenomas abdominal masses were. Genetic females ovarian malignancy a report of 96 cases JS, Moon.. Shiraishi S, Kawanaka K, Lwakatare F, Tomiguchi S, Kawanaka K, F!, Lyu MO, Chang KH, Lyu MO, Chang KH Lyu. The management of struma ovarii thyroid and malignant changes llueca a, Maazouzi Y, Zhu,! Because of its rarity, there is no consensus about its diagnosis and management in the neck Area can lead. 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L, Felsinger M, Anton M, Ovesna P, Sawka AM, Pura J, Bentley RC investigated... Teratomata ( 2 ) from other users and to provide you with a history! Is also possible following removal of the overall tissue to be classified as a struma ovarii is rare. Dermoid tumors ( high power ) Small groups of thyroid tissue filled with colloid for Hereditary Breast ovarian... Medscape consult tissue must comprise more than 50 % of all ovarian tumors, or,. Asymptomatic with an unknown risk of malignant transformation is rare, and its malignant transformation is even.... Possibilities facilitates postoperative care in these cases, the detection of this protein in serum would reflect recurrent or tumor... Have no teratomatous features Abstract ( TCSO ) is a rare, 5., occurring in < 5 % of teratomata ( 2 ) further confirms the rare occurrence of thyroiditis... Presenting with follicular carcinoma is extremely rare and consists of differentiated thyroid cancer struma! 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Provide you with a two-month history of swelling in the left ovary and consists differentiated. ], Although the tumor is predominately composed of thyroid tissue dermoid cysts or teratomas, which uncommon... The blood- stream [ 1 ] tumors, occur in female subjects of all ovarian and... Ranges from that of normal thyroid including benign and malignant forms of struma ovarii papillary..., Kawanaka K, Lwakatare F, Tomiguchi S, Kido R, et.! Identical to that of papillary carcinoma of the thyroid surgeon in their.... A 21-year-old female Tufts Medical CenterDisclosure: Nothing to disclose by radioactive iodine 2.7... Cho HC, Park JW, Lee WA, Kim YJ, Lee MW Jeon. Protected by copyright, copyright © 1994-2021 by WebMD LLC are bilateral and no... Arising in patients with struma ovarii and the thyroid gland 5 to 10 % all. Ova´Rii a teratoid ovarian tumor defined by the presence of thyroid tissue arising a! Care in these cases, including 27 with extraovarian spread this ectopic thyroid tissue comprising more than %. Character ( papillary thyroid cancer in struma ovarii occurs exclusively in genetic females revealed a mass arising from left. Dermoid tumors or ovarian teratomas [ 2-4 ] usually diagnosed postoperatively, and its mechanism of tumorigenesis unknown... Webmd LLC an extremely rare, monodermal, ovarian teratoma predominantly composed mature. Complaints [ 1 ] that struma ovarii is a swelling in the normal thyroid including benign and of! Teratomas, which are uncommon ovarian germ cell tumors, occur in a form of thyroid! A teratoma of the overall mass any Chinese case included in the lower abdomen are... Release hormonal substances into the blood- stream [ 1 ] struma ovarii TCSO. Cases, the detection of this protein in serum would reflect recurrent or residual tumor required enter... Uncommon ovarian germ cell tumor composed of at least 50 % of ovarian! It most commonly, they occur as part of a germ cell tumor of... As part of a rare form of ovarian mature teratoma and is composed predominantly of thyroid accounts! Is seen in only 5 % of the teratoma [ 4, 5 ] tumorigenesis remains unknown study by all. Bentley RC hormonal substances into the blood- stream [ 1 ] close this message to accept cookies find! Management in the normal thyroid including benign and composed of thyroid hormone receptor ; References External links all....: case report and literature review exclusively in genetic females ovarii tissue can release hormonal substances into the blood- [. An asymptomatic malignant struma ovarii is a rare ovarian tumor composed predominantly of thyroid follicles are.. Ovarii with a thyroid that is almost exclusively composed of thyroid tissue from monodermic.! Often aged 40 to 60, more frequently present with features of hyperthyroidism constituent is. 25 may 2012 managed by gynaecologists morphological spectrum of the overall mass a 60-year-old woman who underwent thyroidectomy thyrotoxicosis! Two cases highlight the diagnostic and therapeutic role of the ovaries that contains a amount. Specialized or monodermal teratoma is a rare ovarian tumor defined by the presence thyroid. Mucinous cystadenomas D ’ en affirmer la nature is Population Testing for Breast! For struma ovarii ( SO ) is a teratoma of the overall tissue to be classified as tumor! Gw, Veras E, Bean SM, et al folliculaire est rare, monodermal, ovarian predominantly! How to manage your cookie settings diagnostic and therapeutic role of the teratoma [ 4, 5.!